发明名称 |
METHOD OF PREVENTING RENAL DISEASE AND TREATING SYMPTOMS THEREOF |
摘要 |
The invention relates to novel methods of using 2-methylene-19-nor-20(S)-1,25-dihydroxyvitamin D3 to prevent renal disease, particularly Lupus nephritis, in a subject at risk of developing renal disease. Methods of preventing symptoms of renal disease, such as proteinuria, splenomegaly or glomerular damage are also provided. Methods of treating symptoms of renal disease, including proteinuria and splenomegaly, are also provided. |
申请公布号 |
EP2461815(A1) |
申请公布日期 |
2012.06.13 |
申请号 |
EP20100744767 |
申请日期 |
2010.07.28 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
CLAGETT-DAME, MARGARET;PLUM, LORI;DELUCA, HECTOR, F.;KIM, JAMES, WONKEE |
分类号 |
A61K31/593;A61P13/12 |
主分类号 |
A61K31/593 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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