发明名称 |
PORPHYROMONAS GINGIVALIS ANTIGENS FOR THE DIAGNOSIS AND TREATMENT OF PERIODONTITIS |
摘要 |
The present invention provides a composition for use in raising an immune response directed against Porphyromonas gingivalis. The composition includes a suitable adjuvant and/or acceptable carrier and one substantially purified P. gingivalis immunogen. The immunogen is selected from the group consisting of Antigen 1, Antigen 2, Antigen 3, Antigen 4 and epitope containing fragments thereof, in which: Antigen 1 is an antigen of P. gingivalis and has an internal amino acid sequence: DLENKGEATLLVTFGSSYKAPRETYAKIEKTFAAAYPDQR; Antigen 2 is an antigen of P. gingivalis and has an internal amino acid sequence: DNPDENPLEGDITQTHTEKYVLAED; Antigen 3 is an antigen of P. gingivalis and has an intemal amino acid sequence: DVLLLDVTPLSLGIETMGGVMTYLIDANTTIPKLK; Antigen 4 is an antigen of P. gingivalis and has an internal amino acid sequence: VYNASISAVGNTSAIDPVVQIIHHN.
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申请公布号 |
CA2249746(C) |
申请公布日期 |
2012.06.12 |
申请号 |
CA19972249746 |
申请日期 |
1997.04.01 |
申请人 |
THE UNIVERSITY OF MELBOURNE;THE VICTORIAN DAIRY INDUSTRY AUTHORITY |
发明人 |
REYNOLDS, ERIC CHARLES;SLAKESKI, NADA;HENDTLASS, ANNE |
分类号 |
C12N15/09;C12N15/31;A61K8/64;A61K31/70;A61K38/00;A61K39/00;A61K39/02;A61K39/07;A61K39/395;A61K39/40;A61K48/00;A61K49/00;A61P1/02;A61P25/00;A61Q11/00;C07H21/00;C07K14/195;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12P21/02;C12P21/08;C12Q1/68;G01N33/569 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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