发明名称 |
Nucleoside triphosphate derivative, nucleic acid probe, multilabeled nucleic acid probe, method for production of multilabeled nucleic acid probe, and method for detection of target nucleic acid |
摘要 |
A novel nucleoside triphosphate derivative, a nucleic acid probe, and a multilabeled nucleic acid probe that can detect a target nucleic acid conveniently and with high sensitivity, as well as a method for producing the multilabeled nucleic acid probe, and a method for detecting a target nucleic acid using the multilabeled nucleic acid probe or the nucleic acid probe. A target nucleic acid can be detected conveniently and with high sensitivity by using a transglutaminase (TGase), and by using a multilabeled nucleic acid probe in which a plurality of labeling portions have been introduced in advance by covalent binding, or by introducing a plurality of labeling portions by covalent binding into a nucleic acid probe that has been hybridized with the target nucleic acid. |
申请公布号 |
US8198418(B2) |
申请公布日期 |
2012.06.12 |
申请号 |
US200913003380 |
申请日期 |
2009.07.22 |
申请人 |
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION;THE UNIVERSITY OF TOKUSHIMA;HITACHI ALOKA MEDICAL, LTD. |
发明人 |
KAMIYA NORIHO;NOJI SUMIHARE;HIRAISHI YOSHIYUKI |
分类号 |
C07G3/00;C07H19/04;C07H21/00;C07H21/02;C12P19/34;C12Q1/68 |
主分类号 |
C07G3/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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