发明名称 |
Peptides associated with HLA-DR MHC class II molecule and involved in rheumatoid arthritis |
摘要 |
Antigenic peptides that bind to MHC Class II molecules with the shared epitope referred to as HLA-DR molecules are disclosed. More specifically, are citrullinated antigenic peptides having an increased affinity for HLA-DR molecules and associated with Rheumatoid Arthritis. These novel peptides provide the basis for new methods of diagnosis and treatment of Rheumatoid Arthritis.
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申请公布号 |
US8198401(B2) |
申请公布日期 |
2012.06.12 |
申请号 |
US20040794227 |
申请日期 |
2004.03.05 |
申请人 |
HILL JONATHAN;CAIRNS EWA;BELL DAVID;LONDON HEALTH SCIENCES CENTRE RESEARCH INC. |
发明人 |
HILL JONATHAN;CAIRNS EWA;BELL DAVID |
分类号 |
A61K38/00;C07K2/00;C07K7/00;C07K14/47;C07K14/74 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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