| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: layered pharmaceutical compositins for introduction of two or more pharmaceutically active ingredients involves two layers and an intermediate layer located between the first and second pharmaceutical layers. The first and second pharmaceutical layers contain pharmaceutically active ingredients specified in a group of Bupropion, Naltrexone and Zonisamide. The intermediate layer contains at least one monosaccharide sugar, disaccharide sugar or starch. The intermediate layer is formed for fast dissolution in vivo with the first and second pharmaceutical layers remaining intact, but physically separated. The layered composition is used for effective weight loss, loss of appetite and treatment of the obesity-related conditions. ^ EFFECT: layered pharmaceutical composition under the invention provides maintained predicted dissolution profile of various medical agents. ^ 20 cl, 7 dwg, 3 tbl |
