发明名称 METHOD FOR CELLULAR RNA EXPRESSION
摘要 The present invention relates to enhancing RNA expression in a cell such as a cell transfected with RNA by reducing the activity of RNA-dependent protein kinase (PKR). Thus, the present invention provides methods for expressing RNA in a cell comprising the step of reducing the activity of RNA-dependent protein kinase (PKR) in the cell. Reducing the activity of RNA-dependent protein kinase (PKR) in the cell increases the stability of RNA and/or increases the expression of RNA in the cell.
申请公布号 CA2819522(A1) 申请公布日期 2012.06.07
申请号 CA20112819522 申请日期 2011.12.02
申请人 BIONTECH AG;TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JGU MAINZ GGMBH (TRON);UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ 发明人 SAHIN, UGUR;BEISSERT, TIM;POLEGANOV, MARCO;HERZ, STEPHANIE
分类号 C12N15/67;C12N5/16 主分类号 C12N15/67
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