发明名称 SMALL MOLECULE IMMUNOPOTENTIATOR AND ASSAY FOR THE DETECTION
摘要 <P>PROBLEM TO BE SOLVED: To provide new immune potentiators, immunogenic compositions, new compounds and pharmaceutical compositions, and new methods for administering a vaccine, by administering small molecule immune potentiators in combination with antigens. <P>SOLUTION: The invention provides immunostimulatory compositions comprising a small molecule immuno-potentiator (SMIP) compound and methods of administration thereof. Also methods for administering an SMIP compound in an effective amount to enhance the immune response of a subject to an antigen are provided. Further new compositions and methods for administering SMIP compounds alone or in combination with another agent for the treatment of cancer, infectious diseases and/or allergies/asthma are provided. In a further aspect, the invention relates generally to methods for screening of small molecule immuno-modulatory compositions. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012107074(A) 申请公布日期 2012.06.07
申请号 JP20120054607 申请日期 2012.03.12
申请人 NOVARTIS VACCINES & DIAGNOSTICS INC 发明人 VALIANTE NICHOLAS;XU FENG;JOHANNA JANSEN;SUSAN KAUFMAN
分类号 A61K39/00;A61K31/7056;A61K45/00;A61P11/06;A61P31/12;A61P35/00;A61P37/04;A61P37/08;A61P43/00;C07H19/052 主分类号 A61K39/00
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