发明名称 |
Method and Apparatus for Single Side Bilayer Formation |
摘要 |
An apparatus for single-sided bilayer formation includes a first fluid chamber including a sidewall and a second fluid chamber extending through the sidewall. A barrier wall separates the first and second fluid chambers and includes a nanopore therein across which a planar lipid bilayer (PLB) is formed. In use, an electrolyte is added to the first and second fluid chambers and a lipid/organic solvent mixture is added to the first fluid chamber to form a lipid/organic solvent layer. The electrolyte level within the first fluid chamber is adjusted such that the lipid layer is raised above the barrier wall and a PLB is formed. Electrolyte levels may be adjusted manually or utilizing a fluid level regulator with or without feedback control. Optionally, the apparatus may be in the form of a nanopore array. The apparatus may be incorporated into an ion channel sensing system. |
申请公布号 |
US2012139564(A1) |
申请公布日期 |
2012.06.07 |
申请号 |
US201213350172 |
申请日期 |
2012.01.13 |
申请人 |
ERVIN ERIC N.;BARRALL GEOFFREY ALDEN;ELECTRONIC BIO SCIENCES, LLC |
发明人 |
ERVIN ERIC N.;BARRALL GEOFFREY ALDEN |
分类号 |
G01R27/08;B05C3/00 |
主分类号 |
G01R27/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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