发明名称 |
NOVEL SELECTIVE INHIBITORS OF PROLYLCARBOXYPEPTIDASE |
摘要 |
The present invention relates to compounds of the formulae: Formula (I), (II), (III), (IV), (V), (VI) in which R is C5-C16 alkyl, R1 is Formula (VII), or Formula (VIII) and isosteres and saltes therof. These compounds are serine protease procarboxypeptidase (FRCP) inhibitors and can be used in the field of weight management and in the preparation of medications for the treatment and management of obesity. Further, the present invention relates to new anorexigenic and anti-inflammatory drugs, acting through PRCP-mediated mechanisms. |
申请公布号 |
WO2012075287(A2) |
申请公布日期 |
2012.06.07 |
申请号 |
WO2011US62889 |
申请日期 |
2011.12.01 |
申请人 |
THE UNIVERSITY OF MISSISSIPPI;SHARIAT-MADAR, ZIAEDDIN;RIMOLDI, JOHN, MATTHEW;GADEPALLI, RAMA SARMA, VENKATA SUBBARAHMANYA |
发明人 |
SHARIAT-MADAR, ZIAEDDIN;RIMOLDI, JOHN, MATTHEW;GADEPALLI, RAMA SARMA, VENKATA SUBBARAHMANYA |
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