| 发明名称 |
MODULATOR OF MUSCARINIC RECEPTOR |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a modulator of a muscarinic receptor, a composition comprising such a modulator, and a method therewith for treating a muscarinic receptor mediated disease. <P>SOLUTION: A method of modulating an activity of the muscarinic receptor which is a method of modulating the receptor activity using a compound of formula (I) or (II), or its salt which is pharmaceutically accepted is disclosed. The compound shown by formula (I) or (II), and a pharmaceutical composition containing the compound are disclosed. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012107055(A) |
申请公布日期 |
2012.06.07 |
| 申请号 |
JP20120039210 |
申请日期 |
2012.02.24 |
| 申请人 |
VERTEX PHARMACEUTICALS INC |
发明人 |
MAKINGS LEWIS R;GARCIA-GUZMAN BLANCO MIGUEL;HURLEY DENNIS J;DRUTU IOANA;RAFFAI GABRIEL;BERGERON DANIELE M;NAKATANI AKIKO;TERMIN ANDREAS P;SILINA ALINA |
| 分类号 |
C07D221/20;A61K31/435;A61K31/438;A61K31/439;A61K31/4545;A61K31/55;A61P1/02;A61P1/04;A61P3/04;A61P9/06;A61P11/06;A61P17/02;A61P25/00;A61P25/04;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P27/02;A61P27/06;A61P43/00;C07D401/04;C07D405/06;C07D471/08;C07D471/10;C07D491/107;C07D519/00 |
主分类号 |
C07D221/20 |
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