发明名称 |
CARBOCYCLE-SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS |
摘要 |
The present invention relates to carbocycle-substituted purine and 7-deazapurine compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which DOT1 -mediated protein methylation plays a part, such as cancer and neurological disorders, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
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申请公布号 |
CA2819734(A1) |
申请公布日期 |
2012.06.07 |
申请号 |
CA20112819734 |
申请日期 |
2011.12.05 |
申请人 |
EPIZYME, INC. |
发明人 |
OLHAVA, EDWARD JAMES;CHESWORTH, RICHARD;KUNTZ, KEVIN WAYNE |
分类号 |
C07D471/04;A61K31/52;A61P25/00;A61P35/00;C07D235/14;C07D401/12 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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