<p>The present invention relates to compounds of formula (I): wherein A= formula: (a) or formula: (b); X is oxygen or methylene; Y is C3-6 alkyl or aryl; Z is oxygen or C1-3 alkyl; R1 is hydrogen or C1-3 alkyl; R2 is hydrogen or C1-3 alkyl; the or each R3 is separately C1-3 alkyl or halo; the or each R4 is separately C1-3 alkyl or halo; p is 0 to 4; q is 0 to 4; m is 0 or 1; and n is 1 to 3. These compounds are useful as kinase inhibitors for the treatment of cancer and other diseases.</p>
申请公布号
WO2011023986(A8)
申请公布日期
2012.06.07
申请号
WO2010GB51385
申请日期
2010.08.20
申请人
THE UNIVERSITY OF MANCHESTER;HAMPSON, LYNNE;HAMPSON, IAN;HADFIELD, JOHN, ANTHONY;KEMP, TIMOTHY, PATRICK;MCGOWAN, ALAN, THOMSON