发明名称 METHODS OF TREATING CUTANEOUS FLUSHING USING SELECTIVE ALPHA-2-ADRENERGIC RECEPTOR AGONISTS
摘要 <p>A composition comprising: at least one selective ± 2 adrenergic receptor agonist selected from the group consisting of guanabenz, guanfacine, alpha-methyl DOPA (methydopamine), amphetamine, methylphenidate, lofexidine, moxonidine, dexmedetomidine, mivazerol, and (2-imidazolin-2-ylamino) quinoxaline derivatives, which derivates are formed with an acidic group other than tartrate; and a dermatologically acceptable carrier, for use in treating cutaneous flushing in an individual, wherein the composition is to be administered to said individual via topical dermatological application in an amount sufficient to prevent, reduce, ameliorate or inhibit, cutaneous flushing.</p>
申请公布号 EP1789433(B1) 申请公布日期 2012.06.06
申请号 EP20040778941 申请日期 2004.07.21
申请人 GALDERMA PHARMA S.A. 发明人 SCHERER, WARREN J.
分类号 C07K1/00;A61K31/00;A61K31/498;A61K45/06;A61P5/24 主分类号 C07K1/00
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