Synthesizing cysteine-containing peptides comprises native chemical ligating and/or oxidizing linear, reduced peptide sequences in biocompatible, non-toxic liquid and taking non-viscous ionic liquid for reacting

摘要

Synthesizing cysteine-containing peptides comprises native chemical ligating and/or oxidizing at least one linear, reduced peptide sequences in a biocompatible, non-toxic liquid at room temperature and taking non-viscous ionic liquid independent of peptide chain length in a concentration of at least 3 mM as well as without requiring cooling or limiting to room temperature for reacting.