发明名称 |
Use of apoptosis-specific eIF-5A siRNA to down regulate expression of proinflammatory cytokines to treat sepsis |
摘要 |
The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5-A1, nucleic acids and polypeptides and methods for down regulating pro-inflammatory cytokines in a mammal by administering siRNA against eIF-5A1 to the mammal to treat/prevent sepsis and/or hemorrhagic shock.
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申请公布号 |
US8193158(B2) |
申请公布日期 |
2012.06.05 |
申请号 |
US20070725520 |
申请日期 |
2007.03.20 |
申请人 |
THOMPSON JOHN E.;DINARELLO CHARLES A.;SENESCO TECHNOLOGIES, INC. |
发明人 |
THOMPSON JOHN E.;DINARELLO CHARLES A. |
分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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