| 发明名称 |
pH-sensitive cationic lipids, and liposomes and nanocapsules containing the same |
| 摘要 |
The invention suggests a pH-sensitive cationic lipid with a pKa value between 3.5 and 8, according to the general formula cation-spacer-Y-spacer-X-lipid, wherein Y and X represent linking groups. Furthermore, liposomes are described, which liposomes include said optionally cationic lipids. |
| 申请公布号 |
US8192753(B2) |
申请公布日期 |
2012.06.05 |
| 申请号 |
US20050505107 |
申请日期 |
2005.08.16 |
| 申请人 |
ESSLER FRANK;PANZNER STEFFEN;ENDERT GEROLD;MARINA BIOTECH, INC. |
发明人 |
ESSLER FRANK;PANZNER STEFFEN;ENDERT GEROLD |
| 分类号 |
A61J3/00;A61K9/127;A61J1/14;A61K9/51;A61K31/7088;A61K31/7105;A61K31/711;A61K38/00;A61K47/12;A61K47/16;A61K47/22;A61K47/24;A61K47/34;A61K48/00;A61P3/00;A61P9/00;A61P31/04;A61P31/10;A61P31/12;A61P33/00;A61P35/00;A61P37/00;A61P37/04;A61P37/06;A61P43/00;C07D233/54;C07D233/64;C07D295/088;C07D295/13 |
主分类号 |
A61J3/00 |
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