发明名称 |
Methods for assessing the results of disc-based bioassays with standard computer optical drives |
摘要 |
Methods and systems are described for assessing the results of a bioassay between probe biomolecules and target biomolecules using conventional optical disk drive. particular methods involve: bonding the probe biomolecules to a polycarbonate (PC) surface of an optical disk having digital data comprising error-detection redundancies recorded thereon: introducing the target biomolecules to the PC surface of the optical disk in a vicinity of the bonded probe biomolecules; processing the bioassay to alter a manner in which a read light from the optical disk interacts optically with the optical disk in a vicinity of positive bioassay results where the target biomolecules have bonded to the probe biomolecules; reading the digital data from the optical disk using the optical drive and using the error-redundancies to detect errors in the digital data read by the optical drive; mapping the detected errors to corresponding locations on the optical disk; and determining that positive bioassay results have occurred at the locations of the detected errors. |
申请公布号 |
US8194514(B2) |
申请公布日期 |
2012.06.05 |
申请号 |
US20090920100 |
申请日期 |
2009.03.02 |
申请人 |
YU HUA-ZHONG (HOGAN);LI YUNCHAO;OU MIAO-LING (LILY);SIMON FRASER UNIVERSITY |
发明人 |
YU HUA-ZHONG (HOGAN);LI YUNCHAO;OU MIAO-LING (LILY) |
分类号 |
G11B7/00 |
主分类号 |
G11B7/00 |
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