发明名称 |
OXIDATION-STABILIZED TAMPER-RESISTANT DOSAGE FORM |
摘要 |
A thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising a pharmacologically active ingredient (A), a free physiologically acceptable acid (B) in an amount of from 0.001 wt.-% to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and a polyalkylene oxide (C) having a weight average molecular weight Mw of at least 200,000 g/mol.
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申请公布号 |
US2012136021(A1) |
申请公布日期 |
2012.05.31 |
申请号 |
US201213343846 |
申请日期 |
2012.01.05 |
申请人 |
BARNSCHEID LUTZ;GALIA ERIC;SCHWIER SEBASTIAN;BERTRAM ULRIKE;GEISSLER ANJA;GRIESSMANN KORNELIA;BARTHOLOMAEUS JOHANNES;GRUNENTHAL GMBH |
发明人 |
BARNSCHEID LUTZ;GALIA ERIC;SCHWIER SEBASTIAN;BERTRAM ULRIKE;GEISSLER ANJA;GRIESSMANN KORNELIA;BARTHOLOMAEUS JOHANNES |
分类号 |
A61K31/485;A61K47/34;A61P25/04 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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