发明名称 Peritoneal dialysis methods and apparatus
摘要 A peritoneal-based ("bloodless") artificial kidney processes peritoneal fluid without need for additional fluids ("waterless"). Fluid is separated into a protein-rich stream and a protein-free stream. The protein-rich stream is regenerated using a sorbent assembly, and its protein composition can be modified by removal of selected protein(s) ("dialysate-pheresis"). It is then reconstituted with additives and returned into the peritoneal cavity, thereby reducing protein-loss and providing oncotic-pressure for ultrafiltration. The protein-free stream is used to produce free water, and an alkaline or acid fluid for optimization of the composition of the regenerated stream. The unused protein-free stream can be used to "reverse flush" the separator to maintain its patency and the excess discarded for fluid-balance regulation. Compared to prior art, immobilization of urease allows more protein rich fluid to be regenerated and re-circulated into the peritoneal cavity for toxin removal and allows practicable development of portable and wearable artificial kidneys.
申请公布号 AU2007211317(B2) 申请公布日期 2012.05.31
申请号 AU20070211317 申请日期 2007.01.30
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;U.S. GOVERNMENT: DEPARTMENT OF VETERANS AFFAIRS 发明人 ROBERTS, MARTIN;LEE, DAVID B.N.
分类号 A61M1/00 主分类号 A61M1/00
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