| 发明名称 |
ETHER BENZOTRIAZOLE DERIVATIVES |
| 摘要 |
The present invention is directed to ether benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
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| 申请公布号 |
US2012135977(A1) |
申请公布日期 |
2012.05.31 |
| 申请号 |
US201113247009 |
申请日期 |
2011.09.28 |
| 申请人 |
BESHORE DOUGLAS C.;DUDKIN VADIM;GARBACCIO ROBERT M.;JOHNSON ADAM W.;KUDUK SCOTT D.;SKUDLAREK JASON W.;WANG CHENG;FRALEY MARK E. |
发明人 |
BESHORE DOUGLAS C.;DUDKIN VADIM;GARBACCIO ROBERT M.;JOHNSON ADAM W.;KUDUK SCOTT D.;SKUDLAREK JASON W.;WANG CHENG;FRALEY MARK E. |
| 分类号 |
A61K31/4192;A61K31/437;A61K31/4439;A61K31/454;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61K31/541;A61K31/55;A61K31/551;A61P25/00;A61P25/18;C07D249/18;C07D401/12;C07D403/12;C07D413/12;C07D417/12;C07D471/04 |
主分类号 |
A61K31/4192 |
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