发明名称 |
PROCESS FOR THE PREPARATION OF (2R.3S)-2-(HYDROXYMETHYL) -5-METHOXYTETRAHYDROFURAN-3-OL AND ACETYLATED DERIVATIVES THEREOF, FREE OF PYRANOSE COMPOUNDS |
摘要 |
A method of preparing a ribofuranose derivative essentially free of pyranose compounds includes a step of contacting a solution of MDR containing MDRP as an impurity in a solvent including methanol and/or tetrahydrofuran with at least one alkali metal periodate under conditions sufficient to oxidize at least a portion of the MDRP. MDR containing at most 5 wt% of MDRP based on the total weight of MDR and MDRP may be produced. |
申请公布号 |
WO2012071508(A1) |
申请公布日期 |
2012.05.31 |
申请号 |
WO2011US62038 |
申请日期 |
2011.11.23 |
申请人 |
JOHNSON MATTHEW PUBLIC LIMITED COMPANY;FU, XING;ZUMBRUNN, ALBERCHT |
发明人 |
FU, XING;ZUMBRUNN, ALBERCHT |
分类号 |
C07H3/08;C07H13/04;C07H15/04 |
主分类号 |
C07H3/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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