发明名称 |
Azabicyclo?á3.1.0?å hexane derivatives useful as modulators of dopamine D3 receptors |
摘要 |
The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt thereof:
wherein
€¢ G is phenyl and (R 1 ) p is 4-trifluoromethyl;
€¢ R 2 is hydrogen;
€¢ R 3 is methyl;
€¢ R 4 is 4-pyridazinyl;
processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D 3 receptors, e.g. to treat drug dependency or as antipsychotic agents. |
申请公布号 |
SI2060570(T1) |
申请公布日期 |
2012.05.31 |
申请号 |
SI20050031503T |
申请日期 |
2005.02.21 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
ARISTA LUCA;BONANOMI GIORGIO;CAPELLI ANNA MARIA;DAMIANI FEDERICA;DI FABIO ROMANO;GENTILE GABRIELLA;HAMPRECHT DIETER;MICHELI FABRIZIO;TARSI LUCA;TEDESCO GIOVANNA;TERRENI SILVIA |
分类号 |
A61K31/403;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D413/14;C07D417/14;C07D495/04 |
主分类号 |
A61K31/403 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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