发明名称 BISPECIFIC BINDING MOLECULES FOR ANTI-ANGIOGENESIS THERAPY
摘要 <p>Bispecific binding molecules, in particular immunoglobulin single variable domains such as VHHs and domain antibodies, comprising a VEGF-binding component and a Dll4-binding component in one molecule. Pharmaceutical compositions containing same and their use in the treatment of diseases that are associated with VEGF- and Dll4-mediated effects on angiogenesis. Nucleic acids encoding the bispecific binding molecules, host cells and methods for preparing same.</p>
申请公布号 IL218542(D0) 申请公布日期 2012.05.31
申请号 IL20120218542 申请日期 2012.03.08
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人
分类号 C07K 主分类号 C07K
代理机构 代理人
主权项
地址