发明名称 |
PLASMA TREATMENT FOR GROWTH FACTOR RELEASE FROM CELLS AND TISSUES |
摘要 |
Aspects of the present invention are related to methods comprising contacting an endothelial cell in an endothelial cell population with a non-thermal plasma to release an angiogenic growth factor. The released angiogenic growth factor may induce endothelial cell proliferation. In certain embodiments, the angiogenic growth factor is fibroblast growth factor-2. Preferably, the non-thermal plasma may be an atmospheric pressure dielectric barrier discharge. Additional aspects of the present invention are directed to methods for treating a disease comprising promoting angiogenesis by contacting an endothelial cell in a endothelial cell population with a non-thermal plasma to release an angiogenic growth factor. The angiogenic growth factor may induce endothelial cell proliferation. Further aspects of the present invention are directed to methods for treating a disease comprising inhibiting angiogenesis by contacting an endothelial cell in a endothelial cell population with a non-thermal plasma to reduce the number of endothelial cells in the population. |
申请公布号 |
US2012135390(A1) |
申请公布日期 |
2012.05.31 |
申请号 |
US201013256558 |
申请日期 |
2010.03.16 |
申请人 |
CLYNE ALISA MORSS;FRIEDMAN GENNADY;FRIDMAN ALEXANDER;KALGHATGI SAMEER;DREXEL UNIVERSITY |
发明人 |
CLYNE ALISA MORSS;FRIEDMAN GENNADY;FRIDMAN ALEXANDER;KALGHATGI SAMEER |
分类号 |
A01N1/02;C12N13/00 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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