| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide methods and compositions for reducing viral genome amounts in a target cell. <P>SOLUTION: In the methods, the activity of miRNA is inhibited in a manner sufficient to reduce the amount of viral genome in the target cell, e.g. by a process of introducing an miRNA inhibitory agent in the target cell. Also, pharmaceutical compositions, kits and systems for use in practicing the methods are provided. The invention finds use in a variety of applications, including the treatment of subjects suffering from a viral mediated disease condition, e.g. an HCV-mediated disease condition or the like. <P>COPYRIGHT: (C)2012,JPO&INPIT |
