发明名称 |
NOVEL MARKERS FOR CHRONIC KIDNEY DISEASE |
摘要 |
The present invention relates to a method for determining the progression of chronic kidney disease in a subject suspected of having chronic kidney disease, comprising of determining the expression levels of at least one marker selected from (a) FGF23; and (b) adiponectin in a biological sample. Furthermore, the present invention relates to a use of a specific detection molecule for FGF23 or adiponectin for the preparation of a diagnostic composition for the detection of chronic kidney disease or the progression of chronic kidney diseases in a subject suspected to suffer from said disease. In particular, the present invention also provides for use of FGF23 and/or of adiponectin as an in vitro marker for the presence, absence or progression of a chronic kidney disease and kits comprising a specific detection molecule for FGF23 or a specific detection molecule for adiponectin for use in the method of the present invention.
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申请公布号 |
US2012135428(A1) |
申请公布日期 |
2012.05.31 |
申请号 |
US201113280719 |
申请日期 |
2011.10.25 |
申请人 |
KRONENBERG FLORIAN;KOLLERITS BARBARA;FLISER DANILO |
发明人 |
KRONENBERG FLORIAN;KOLLERITS BARBARA;FLISER DANILO |
分类号 |
G01N33/566;C07K16/22;C07K16/26 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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