发明名称 Treatment of CNS Disorders with trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine
摘要 Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
申请公布号 US2012136065(A1) 申请公布日期 2012.05.31
申请号 US201213365565 申请日期 2012.02.03
申请人 JERUSSI THOMAS P.;FANG QUN KEVIN;CURRIE MARK G.;SUNOVION PHARMACEUTICALS INC. 发明人 JERUSSI THOMAS P.;FANG QUN KEVIN;CURRIE MARK G.
分类号 A61K31/135;A61P25/28;C07C211/42 主分类号 A61K31/135
代理机构 代理人
主权项
地址