发明名称 REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES
摘要 The present invention provides a process for high yield regioselective synthesis of DTPA derivatives that eliminates the need for ion exchange chromotographic separation of intermediates. Moreover, as this process yields a single regioisomer of the chelate, it provides for the regiospecific synthesis of desired chelates useful as radiolabeling agents.
申请公布号 PL211510(B1) 申请公布日期 2012.05.31
申请号 PL20000350903 申请日期 2000.03.02
申请人 BIOGEN IDEC INC. 发明人 CHINN PAUL;GYORKOS ALBERT;LABARRE MICHAEL J.;RUHL STEVE;RYSKAMP THOMAS
分类号 C07C331/28;A61K51/10 主分类号 C07C331/28
代理机构 代理人
主权项
地址