| 发明名称 |
INTERMEDIATE COMPOUNDS AND PROCESSES FOR THE PREPARATION OF QUINOLINE DERIVATIVES SUCH AS LAQUINIMOD SODIUM |
| 摘要 |
<p>The present invention relates to processes for the preparation of quinoline-3 -carboxamide derivatives, such as sodium 5-chloro-3-(ethylphenylcarbamoyl)-l-methyl-2- oxo-l,2-dihydroquinolin-4-olate (Laquinimod sodium). The present invention further relates to intermediates formed in such processes.</p> |
| 申请公布号 |
CA2815935(A1) |
申请公布日期 |
2012.05.31 |
| 申请号 |
CA20112815935 |
申请日期 |
2011.11.28 |
| 申请人 |
MAPI PHARMA LTD. |
发明人 |
MAROM, EHUD;MIZHIRITSKII, MICHAEL;RUBNOV, SHAI |
| 分类号 |
C07C233/54;A61K31/4704;A61P37/00;C07C229/56;C07C233/33;C07C235/80;C07D215/56 |
主分类号 |
C07C233/54 |
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