发明名称 |
DENDRITIC CELL VACCINES FOR ASPARAGINYL - BETA - HYDROXYLASE EXPRESSING TUMORS |
摘要 |
A vaccine containing AAH-loaded mature dendritic cells for treatment of AAH-expressing tumors in mammalian subjects. A method of producing primed dendritic cells is carried out by contacting isolated dendritic cells with an antigen such as AAH. Following the antigen-contacting step, the dendritic cells are contacted with a combination of cytokines such as GM-CSF and IFN-γ. |
申请公布号 |
EP2456458(A2) |
申请公布日期 |
2012.05.30 |
申请号 |
EP20100735417 |
申请日期 |
2010.07.23 |
申请人 |
RHODE ISLAND HOSPITAL |
发明人 |
SHIMODA, MASAFUMI;WANDS, JACK, R. |
分类号 |
A61K39/00;C07K14/705 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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