发明名称 |
UNIVERSAL MICROBIAL DIAGNOSIS, DETECTION, QUANTIFICATION, AND SPECIMEN-TARGETED THERAPY |
摘要 |
Microbial ecology of a specimen is evaluated using an approach (Level I) that utilizes nucleic acid amplification with specific gene primers that will identify panels of microorganisms and antibiotic-resistance factors generating a diagnostic report (optionally with quantification of each microorganism or antibiotic-resistance factor) and an approach (Level II) that utilizes universal or semi-universal primers to amplify conserved genes at a general or specific taxonomic level that are tagged specimen specifically using a genetic or chemical marker that is specific to the specimen from which it was derived, then sequencing the amplified products with highly-parallel, high-throughput technology to provide comprehensive sequences of the microbial population in the specimen followed by analysis of this sequence information and specific targeted information from Level I and/or Level II to generate a comprehensive analysis, interpretation, and/or diagnostic report. |
申请公布号 |
EP2456891(A1) |
申请公布日期 |
2012.05.30 |
申请号 |
EP20100802574 |
申请日期 |
2010.07.26 |
申请人 |
SOUTHWEST REGIONAL PCR, LLC |
发明人 |
WOLCOTT, RANDALL D.;KENNEDY, JOHN P.;DOWD, SCOT E. |
分类号 |
C12Q1/68;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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