发明名称 |
DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE |
摘要 |
The present invention relates to a compound of General Formula (I) below, among others. In the Formula, Ar1 is an optionally substituted aryl or heteroaryl group; R1 is a hydrogen atom, an optionally substituted C1-C6 alkyl group, or an optionally substituted aryl, aralkyl, or heteroaryl group; R2 is an optionally substituted aryl, aralkyl, or heteroaryl group; and R3 is a hydrogen atom or a C1-C6 alkyl group. A compound of the present invention has an excellent Wee1 kinase inhibiting effect, and is therefore useful in the filed of medicine, particularly in various types of cancer therapy. |
申请公布号 |
EP2376493(A4) |
申请公布日期 |
2012.05.30 |
申请号 |
EP20090831988 |
申请日期 |
2009.12.09 |
申请人 |
MSD K.K. |
发明人 |
BAMBA, MAKOTO;FURUYAMA, HIDETOMO;SAKAMOTO, TOSHIHIRO;SUNAMI, SATOSHI;TAKAHASHI, KEIJI;YAMAMOTO, FUYUKI;YOSHIZUMI, TAKASHI |
分类号 |
C07D487/04;A61K31/519;A61K31/5377;A61K41/00;A61P35/00;A61P35/02;A61P43/00;C07D519/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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