| 发明名称 |
SINGLE-CHAIN MULTIPLE ANTIGEN-BINDING MOLECULE, ITS PREPARATION AND USE |
| 摘要 |
The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.
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| 申请公布号 |
CA2268258(C) |
申请公布日期 |
2012.05.29 |
| 申请号 |
CA19992268258 |
申请日期 |
1999.04.08 |
| 申请人 |
HOECHST MARION ROUSSEL DEUTSCHLAND GMBH |
发明人 |
KONTERMANN, ROLAND;SEDLACEK, HANS-HARALD;MULLER, ROLF |
| 分类号 |
C12N15/00;C12N15/13;A61K31/00;A61K31/70;A61K35/12;A61K35/74;A61K35/76;A61K38/00;A61K39/00;A61K39/395;A61K48/00;A61P7/00;A61P25/00;A61P31/00;A61P35/00;A61P37/00;C07K16/00;C07K16/30;C07K16/40;C07K16/46;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/62;G01N33/531 |
主分类号 |
C12N15/00 |
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