发明名称 |
IMMUNOGLOBULIN FUSION PROTEINS |
摘要 |
The present invention relates to novel methods for making fusion proteins comprising a cytokine or growth factor fused to an immunoglobulin domain. The growth factor/cytokine can be fused directly to an immunoglobulin domain or through a peptide linker. The purified growth factor/cytokine-IgG fusion proteins produced by the novel methods are biologically active and can be used to treat diseases for which the non-fused growth factor/cytokine are useful.
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申请公布号 |
CA2379388(C) |
申请公布日期 |
2012.05.29 |
申请号 |
CA20002379388 |
申请日期 |
2000.07.13 |
申请人 |
BOLDER BIOTECHNOLOGY INC. |
发明人 |
COX, GEORGE N., III;DOHERTY, DANIEL H. |
分类号 |
A61K39/395;C12N15/09;A61K38/00;A61K39/00;A61P7/00;A61P7/04;A61P25/00;A61P31/12;A61P35/00;C07K1/00;C07K14/475;C07K14/505;C07K14/52;C07K14/535;C07K14/54;C07K14/56;C07K14/565;C07K14/61;C07K16/00;C07K16/18;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;C12R1/91 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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