| 发明名称 |
RNAi modulation of APOB and uses thereof |
| 摘要 |
The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides. |
| 申请公布号 |
US8188061(B2) |
申请公布日期 |
2012.05.29 |
| 申请号 |
US20100728139 |
申请日期 |
2010.03.19 |
| 申请人 |
SOUTSCHEK JUERGEN;VORNLOCHER HANS-PETER;HADWIGER PHILIPP;ELBASHIR SAYDA;ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
SOUTSCHEK JUERGEN;VORNLOCHER HANS-PETER;HADWIGER PHILIPP;ELBASHIR SAYDA |
| 分类号 |
A61K31/70;C07H21/02;C07H21/04;C12Q1/68 |
主分类号 |
A61K31/70 |
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