发明名称 |
Non-lamellar compositions of DOPE and P80 |
摘要 |
The present invention relates to particulate compositions comprising at least 50% of dioleoyl phosphatidyl ethanolamine (DOPE) and 1 to 50% of Polysorbate 80 (P80). All parts are by weight relative to the sum of the weights of a+b and the compositions comprise non-lamellar particles or form non-lamellar particles when contacted with an aqueous fluid. The compositions have advantageous stability and low toxicity and the invention also relates to pharmaceutical compositions thereof.
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申请公布号 |
US8187629(B2) |
申请公布日期 |
2012.05.29 |
申请号 |
US20050586778 |
申请日期 |
2005.01.21 |
申请人 |
BARAUSKAS JUSTAS;TIBERG FREDRIK;CAMURUS AB |
发明人 |
BARAUSKAS JUSTAS;TIBERG FREDRIK |
分类号 |
A61K9/127;A61K31/66 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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