| 摘要 |
<p>Disclosed are irreversible tyrosine kinase inhibitor compounds of Formula (I) (1H-pyrazolo[3,4-d] pyrimidine), wherein the substituents are as described within the specification. Further disclosed is a pharmaceutical composition comprising a therapeutically effective amount of a compound of Formula (I), and the use of a compound of Formula (I) for the manufacture of a medicament for the treatment of an autoimmune disorder, a heteroimmune disorder, inflammation, rheumatoid arthritis, lupus, allergies, type I hypersensitivity, allergic conjunctivitis, allergic rhinitis, atopic dermatitis, B-cell lymphoma, diffuse large B cell lymphoma, follicular lymphoma, chronic lymphocytic leukemia, or a combination thereof.</p> |
