TENOCYTE CONTAINING BIOSCAFFOLDS AND TREATMENT USING THE SAME

摘要

Disclosed is the use of a tenocyte seeded bioscaffold in the preparation of a medicament for the treatment of rotator cuff tear in a mammalian subject, wherein the tenocyte seeded bioscaffold was prepared by: (i) selectively expanding tenocytes in vitro in culture medium comprising insulin or a functional derivative and a glucocorticoid or a glucocorticoid-like molecule to produce a culture of expanded tenocytes; and (ii) seeding a bioscaffold with said culture of expanded tenocytes.