TRANSPLANTATION OF HUMAN NEURAL CELLS FOR TREATMENT OF NEURODEGENERATIVE CONDITIONS

摘要

PROBLEM TO BE SOLVED: To provide a method of treating neurodegenerative conditions based on a fact that neural stem cells may be transplanted to a site of and/or remote from the site of neuron degeneration.

SOLUTION: The method can include isolation of neural stem cells from a site where specific types of neurons corresponding to the neurons to be replaced are generated. The method can include isolation of neural stem cells secreting growth factors affecting the growth and/or regeneration of specific types of neurons. There is disclosed a method of treating such disorders including several neurodegenerative disorders arising from the lack of cells that produce particular neurotransmitters in neural circuitry by transplanting exogenously cultured and proliferated neural precursors which, upon transplantation into a neural tissue, differentiate into neurons capable of integrating and producing neurotransmitters in sufficient quantities and in a sufficient manner to overcome the symptoms associated with the neurodegeneration.

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