COMPOUNDS FOR THE MODULATION OF PDZ-BINDING KINASE (PBK) EXPRESSION
摘要
The present invention relates to oligomer compounds (oligomers), which target PBK mRNA in a cell, leading to reduced expression of PBK. Reduction of PBK expression is beneficial for the treatment of diseases or disorders associated with overexpression or undesirably high levels of PBK, such as cancer.
申请公布号
WO2012066093(A1)
申请公布日期
2012.05.24
申请号
WO2011EP70381
申请日期
2011.11.17
申请人
SANTARIS PHARMA A/S;HOEG, ANJA;UZCATEGUI, NATHALIE;HEDTJAERN, MAJ