METHODS AND COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE TO EGFRVIII
摘要
The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.
申请公布号
WO2012068360(A1)
申请公布日期
2012.05.24
申请号
WO2011US61164
申请日期
2011.11.17
申请人
ADURO BIOTECH;PROVIDENCE HEALTH & SERVICES-OREGON D/B/A PROVIDENCE PORTLAND MEDICAL CENTER;LAUER, PETER, M.;BAHJAT, KEITH