发明名称 REGIMENS FOR TREATMENTS USING ANTI-IGF ANTIBODIES
摘要 Without limitation, this disclosure relates to methods of treating cell proliferation disorders, neoplastic disorders, cancers, tumors and the like using anti-IGF antibodies, or antigen binding fragments thereof. Disclosed herein are methods of treating cancer in a patient, for example a human patient, comprising administering to the patient at least two doses of an antibody which binds both IGF-I and/or IGF-II. The doses are separated by about a week, or by about three weeks, and each dose comprises an amount of antibody greater than about 0.5 mg kg of patient body mass and less than about 50 mg per kg of patient body mass.
申请公布号 WO2012068148(A1) 申请公布日期 2012.05.24
申请号 WO2011US60839 申请日期 2011.11.15
申请人 MEDIMMUNE, LLC;VINER, JAYE;CHANG, YONG;MCDEVITT, JENNIFER 发明人 VINER, JAYE;CHANG, YONG;MCDEVITT, JENNIFER
分类号 A61K39/395;A61K39/00;C12P21/08 主分类号 A61K39/395
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