发明名称 COMPOSITIONS AND METHODS FOR KINASE-MEDIATED CYTOPROTECTION AND ENHANCED CELLULAR ENGRAFTMENT AND PERSISTENCE
摘要 Disclosed are methods of protecting cells, especially non-vascular system, non-hematopoietic cells and tissues, from apoptosis and enhancing their engraftment, survival, and/or persistence by providing enhanced levels of PIM activity for the cell, including PIM-1 activity. Also disclosed are cells that have been engineered to express enhanced levels of PIM kinase, and methods of administering those cells to vertebrates.
申请公布号 US2012128631(A1) 申请公布日期 2012.05.24
申请号 US201013319512 申请日期 2010.05.19
申请人 SUSSMAN MARK A.;SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION, DBASAN DIEGO STATE UNIVERSITY (SDSU) RESEARCH 发明人 SUSSMAN MARK A.
分类号 A61K35/00;A61P1/16;A61P1/18;A61P5/00;A61P11/00;A61P13/12;A61P19/04;A61P19/08;A61P25/00;C12N5/071;C12N15/54 主分类号 A61K35/00
代理机构 代理人
主权项
地址