KIT FOR DIAGNOSING COLORECTAL CANCER AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF COLORECTAL CANCER

摘要

The present invention relates to: a composition for diagnosing colorectal cancer containing a formulation for measuring the expression level of a chromosome 1 open reading frame 135 (C1orf135) gene mRNA or the protein thereof; a kit for diagnosing colorectal cancer containing the composition; a method for providing information on diagnosis of colorectal cancer, the method comprising a step for measuring the expression level of a C1orf135 gene mRNA or the expression level of the protein coded by the gene; a pharmaceutical composition for the prevention or the treatment of colorectal cancer, the composition comprising an expression inhibitor for a C1orf135 gene or an activity inhibitor for the protein thereof; and a method for screening a therapeutic agent for colorectal cancer. The present invention enables the accurate diagnosis of colorectal cancer by providing a gene specific to colorectal cancer, and a diagnostic marker for determining the metastasis and prognosis of colorectal cancer, and can be useful in the diagnosis and prognosis management of colorectal cancer. Also, the present invention enables the development of new bio-medicines having fewer side effects and customized anticancer drugs by providing a colorectal cancer-specific therapeutic agent capable of inhibiting the gene.