| 摘要 |
Inosine is prepared by fermentation of an aqueous culture medium with a strain of bacteria of the genus Bacillus which is capable of producing inosine and employing in the culture medium potassium ions in an amount of at least 500 mg/dl. and/or magnesium ions in an amount of at least 400 mg/dl. The invention also includes a process for preparing inosine in the presence of gaseous or aqueous ammonia, and including in the culture medium calcium ions in an amount of more than 1 g/l. The potassium and magnesium ions may be added in the form of their salts, and calcium ions may be provided by, e.g. calcium chloride. Specified strains of Bacilli are Bacillus Subtilis strains.
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