Medical preparations for the treatment of alpha-galactosidase a deficiency
摘要
<p>The invention provides highly purified ±-Gal A, and various methods for purifying it; ±-Gal A preparations with altered charge and methods for making those preparations; ±-Gal A preparations that have an extended circulating half-life in a mammalian host, and methods for making same; and methods and dosages for administering an ±-Gal A preparation to a subject.</p>
申请公布号
EP2186902(B1)
申请公布日期
2012.05.23
申请号
EP20100152432
申请日期
2000.03.09
申请人
SHIRE HUMAN GENETIC THERAPIES, INC.
发明人
SELDEN, RICHARD;BOROWSKI, MARIANNE;KINOSHITA, CAROL M.;TRECO, DOUGLAS A.;WILLIAMS, MELANIE D.;SCHUETZ, THOMAS J.;DANIEL, PETER FRANCIS