发明名称 |
PH-SENSITIVE POLYMERSOME AND PREPARING THEREOF |
摘要 |
PURPOSE: A pH-sensitive copolymer and a polymersome using the same are provided to express sustained release according to pH condition in human body. CONSTITUTION: A pH-sensitive polymersome contains copolymers including 10-70 wt% of poly(beta-amino ester), 30-80 wt% of polylactic acid-based compounds, and 1-10 wt% of polyethylene glycol-based compounds. The molar ratio of the poly(beta-amino ester) compounds, polylactic acid-based compounds, and polyethylene glycol-based compounds is 10:24:1-10:5:1. The polymersomes contain copolymers including biocompatible and pH-sensitive compounds(A), hydrophilic and biodegradable compounds(B), and hydrophobic and biodegradable compounds(C).
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申请公布号 |
KR20120051495(A) |
申请公布日期 |
2012.05.22 |
申请号 |
KR20100112964 |
申请日期 |
2010.11.12 |
申请人 |
SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION |
发明人 |
LEE, DOO SUNG;KIM, BONG SUP;KIM, NIN SANG;CHO, YOON KI |
分类号 |
A61K47/30;A61K49/06;C08G63/08;C08G65/00 |
主分类号 |
A61K47/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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