摘要 |
PURPOSE: A novel synthetic method for sumadain A or derivative thereof is provided to quickly and efficiently prepare sumadain A and derivative thereof with excellent physiological activity. CONSTITUTION: A method for synthesizing sumadain A or derivative thereof comprises: a step of cyclizing 2,4,6-trihydroxyacetopenone and alpha,beta-unsaturated aldehyde under the presence of diacetate at 90-110°C for 8-12 hours; and a step of performing aldole condensation reaction of the reactant with benzaldehyde at room temperature for 42-56 hours. The sumadain A or derivative thereof is denoted by chemical formula 1 or 2.
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