| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to medicine, more specifically to a pharmaceutical gel of ketoprofen with analgesic and anti-inflammatory action. The presented gel contains ketoprofen (1.0-6.0 wt %) and target additives: ethanol - 10.0-20.0 wt %, propyleneglycol - 10.0-20.0 wt %, UV filter Escalol 567 - 1.0-40.0 wt %, cyclomethicone DC 345 - 5.0-20.0 wt %, organosilicone emulsifier DC 5329 - 1.0-4.0 wt %, acrylate emulsion of copolymer Salcare SC80 - 1.0-3.5 wt %, trometamol - 1.0-2.5 wt %, fragrance - 0.2-0.4 wt %, preservative SHAROMIX MCI - 0.1-0.5 wt %, purified water - to 100.0 wt %. ^ EFFECT: due to said composition of target additives, the invention provides stabilisation of photosensitive ketoprofen and its improved penetration in derma, ethanol reduction in the gel, improved gel protection against microorganisms. ^ 1 tbl, 3 ex |
