Methods of screening for agents that modulate the activity of a mechanically-activated cation channel are provided. Also provided are compositions and methods for ameliorating pain by antagonizing or inhibiting mechanically-activated cation channels.
申请公布号
WO2012027389(A3)
申请公布日期
2012.05.18
申请号
WO2011US48836
申请日期
2011.08.23
申请人
IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY;THE SCRIPPS RESEARCH INSTITUTE;COSTE, BERTRAND;PATAPOUTIAN, ARDEM